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Extractive electrospray ionization : ウィキペディア英語版 | Extractive electrospray ionization
Extractive electrospray ionization (EESI)〔Chen, H., A. Venter, and R.G. Cooks, Extractive electrospray ionization for direct analysis of undiluted urine, milk and other complex mixtures without sample preparation. Chemical Communications, 2006(19): p. 2042-2044. 〕〔 Chen, H., et al. Extractive Electrospray Ionization Time-of-Flight Mass Spectrometry for Direct Fingerprinting of Ambient Samples. in 17th International Mass Spectrometry Conference. 2006. Prague.〕 is a spray-type, ambient ionization source〔Chen, H., G. Gamez, and R. Zenobi, What Can We Learn from Ambient Ionization Techniques? Journal of The American Society for Mass Spectrometry, 2009. 20(11): p. 1947-1963.〕〔Cooks, R.G., et al., Ambient Mass Spectrometry. Science, 2006. 311(5767): p. 1566-1570.〕〔Harris, G.A., A.S. Galhena, and F.M. Ferna?ndez, Ambient Sampling/Ionization Mass Spectrometry: Applications and Current Trends. Analytical Chemistry, 2011. 83(12): p. 4508-4538.〕〔Huang, M.-Z., et al., Ambient Ionization Mass Spectrometry. Annual Review of Analytical Chemistry, 2010. 3(1): p. 43-65.〕〔Van Berkel, G.J., S.P. Pasilis, and O. Ovchinnikova, Established and emerging atmospheric pressure surface sampling/ionization techniques for mass spectrometry. Journal of Mass Spectrometry, 2008. 43(9): p. 1161-1180.〕 in mass spectrometry that uses two colliding aerosols, one of which is generated by electrospray. In standard EESI, syringe pumps provide the liquids for both an electrospray and a sample spray. In neutral desorption EESI (ND-EESI), the liquid for the sample aerosol is provided by a flow of nitrogen. == Principle of operation == A ND-EESI experiment is simple in concept and implementation. A room temperature (20 °C) nitrogen gas stream is flowed through a narrow opening (i.d.~0.1 mm) to form a sharp jet targeted at a surface. The nitrogen molecules desorb analytes from the surface. The jet is only 2–3 mm above the surface, and the gas flow is about 200 mL/min with gas speeds around 300 m/s. The sample area is about 10 mm2.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Extractive electrospray ionization」の詳細全文を読む
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